Buffalo Chicken Grilled Cheese: 7 Flavorful Twists to Try

Posted on November 18, 2025

If you’re looking for a sandwich that’s bursting with flavor and oh-so-easy to whip up, then let me introduce you to my Buffalo Chicken Grilled Cheese! This delightful creation combines the spicy kick of buffalo chicken with the gooey goodness of melted cheese, all sandwiched between crispy, buttery bread. I mean, who doesn’t love that combo? The first time I made this, I was just trying to use up some leftover chicken, and wow, it turned into a household favorite overnight! It’s perfect for a quick lunch, a game day snack, or even a cozy dinner. Trust me, once you take a bite, you’ll be hooked on that spicy, cheesy goodness! Plus, it takes less than 30 minutes to make, which is a total win in my book!

Ingredients List

2 slices of your favorite bread (I love using sourdough or whole grain for that extra texture!)
1 cup cooked shredded chicken (leftover rotisserie chicken works like a charm!)
1/4 cup buffalo sauce (adjust this based on how spicy you like it—go wild if you’re feeling adventurous!)
1/2 cup shredded cheese (I usually go for a blend of sharp cheddar and mozzarella for that melty goodness)
1 tablespoon butter (because butter makes everything better, right?)

How to Prepare Buffalo Chicken Grilled Cheese

Alright, let’s get down to business and make this mouthwatering Buffalo Chicken Grilled Cheese! I promise it’s super simple and so satisfying. Follow these steps, and you’ll be enjoying your sandwich in no time!

Step 1: Mix the Chicken

First up, grab that cooked shredded chicken and toss it in a bowl. Pour in the buffalo sauce and mix it all together until the chicken is nice and coated. You want a good balance of flavor here, so make sure every piece is covered! If you like it spicy, feel free to add a little more sauce—trust me, it’s hard to go wrong with this!

Step 2: Prepare the Bread

Next, let’s get our bread ready. Take your slices and spread butter on one side of each. This is key to achieving that golden, crispy crust. Now, heat up your skillet over medium heat and place one slice of bread in the skillet, butter side down. It’s like a cozy little bed for our sandwich!

Step 3: Assemble the Sandwich

Now comes the fun part—assembling! On top of the bread in the skillet, layer that delicious chicken mixture evenly, followed by a generous sprinkle of shredded cheese. Then, take the second slice of bread and place it on top, butter side up. This layering is what creates that melty, cheesy experience we all crave!

Step 4: Cook to Perfection

Time to cook! Keep the heat at medium and let that sandwich sizzle away for about 3-4 minutes until the bottom is golden brown. Carefully flip it over with a spatula and cook the other side for another 3-4 minutes. You want that cheese to melt and the bread to be perfectly crispy. Once both sides are golden, remove it from the skillet and let it cool for a minute before slicing. Oh boy, the aroma is going to be irresistible!

Tips for Success

Alright, let’s make sure your Buffalo Chicken Grilled Cheese turns out absolutely perfect! First off, don’t skip the buttering step—both sides of the bread need a nice coat for that golden crust. If you find your cheese isn’t melting as quickly as you’d like, try covering the skillet with a lid for a minute or two; it really helps those cheesy dreams come true!

Also, feel free to customize this beauty! Want more heat? Add jalapeños or a sprinkle of cayenne pepper to the chicken mix. If you’re feeling adventurous, throw in some diced celery for that classic buffalo wing crunch. Just remember, balance is key—too much sauce can make it soggy, so start with a little and adjust to your liking. Trust me, these little tweaks can take your sandwich from great to phenomenal!

Variations of Buffalo Chicken Grilled Cheese

Now, let’s get creative with our Buffalo Chicken Grilled Cheese! There are so many fun ways to switch things up and make this sandwich uniquely yours. First off, try using different types of bread—like a crusty ciabatta or a soft brioche for a sweeter touch. You could even go for a tortilla wrap if you’re in the mood for something lighter!

When it comes to cheese, don’t be afraid to experiment! Pepper jack adds a delightful kick, while bleu cheese crumbles can bring that classic buffalo flavor right into the mix. Feeling indulgent? Mix in some cream cheese for an extra creamy filling. And for those who love a crunch, consider adding some crispy bacon or even a handful of chopped pickles! The possibilities are endless, and each variation can lead to a whole new flavor experience. So, go ahead and have fun with it!

Nutritional Information

When it comes to enjoying your Buffalo Chicken Grilled Cheese, you’ll find it’s not only delicious but also relatively light! Each sandwich packs a punch with about 450 calories, which is pretty reasonable for such a satisfying meal. You’ll also get around 30 grams of protein to keep you full and energized. Just keep in mind, the sodium can be on the higher side at about 800 mg, so it’s something to consider if you’re watching your intake. Overall, it’s a tasty treat that fits nicely into a balanced diet, especially if you pair it with a fresh salad or some veggies on the side!

FAQ Section

Can I use leftover chicken?

Absolutely! Leftover chicken is actually perfect for this Buffalo Chicken Grilled Cheese. Shredded rotisserie chicken is a great choice since it’s already cooked and super flavorful. Just toss it with the buffalo sauce, and you’re good to go! Using leftover chicken not only saves time but also cuts down on food waste—win-win!

What type of cheese works best?

When it comes to cheese for your Buffalo Chicken Grilled Cheese, I love a blend of sharp cheddar and mozzarella. The cheddar gives that robust flavor, while mozzarella adds that gooey, melty goodness we all crave! If you’re feeling adventurous, pepper jack is a fantastic option for an extra kick, or you could even throw in some crumbled bleu cheese for that classic buffalo taste. Experiment and find your favorite combo!

Can I make this in advance?

While this sandwich is best enjoyed fresh, you can prepare some elements in advance! Mix the shredded chicken with buffalo sauce and store it in the fridge for up to two days. When you’re ready to enjoy your Buffalo Chicken Grilled Cheese, just assemble and cook it right before you eat. This way, you’ll have a quick and delicious meal on hand without sacrificing that fresh flavor!

Why You’ll Love This Recipe

Quick to make—ready in just 20 minutes!
Packed with bold flavors that satisfy your cravings
Perfect for lunch, dinner, or a late-night snack
Customizable to your taste—adjust the spice and cheese!
Easy to whip up with simple ingredients you probably have on hand
Great for meal prep; just store the chicken mixture ahead of time
A fun twist on a classic grilled cheese that everyone will love